Mortality on Hemodiafiltration Compared to High-Flux Hemodialysis: A Brazilian Cohort Study

The study included 8,391 patients: 6,787 receiving only high-flux HD, 2,836 receiving HDF, among whom 1,222 had migrated from high-flux HD to HDF during the follow-up period. The 2-year survival rates in these groups were 81.2% and 77.9%, respectively (P<0.001). In this large cohort study conducted in Brazil, patients treated with HDF, compared with those treated with conventional high-flux HD, exhibited a lower risk of all-cause and cardiovascular mortality.