Rituximab in Addition to Plasma Exchange, Cyclophosphamide, and Steroids for the Treatment of Anti-glomerular Basement Membrane (GBM) Disease

A two-center retrospective study of 78 anti-GBM disease patients found that adding rituximab to standard plasma exchange/cyclophosphamide/steroid therapy did not significantly improve survival or kidney outcomes, though it allowed lower cumulative cyclophosphamide doses.