Parvovirus-induced pancytopenia in chronic kidney disease: a diagnostic challenge
Pancytopenia results from diverse underlying conditions. Parvovirus B19 can directly suppress bone marrow and mimic sepsis or drug-induced cytopenia. We…
Authors
Majed A.B. Momin; Gutha S. Reddy; Abhijeet Ingle
Citation
Arab J Nephrol Transplant. 2026;8(3):121–122. doi: 10.4103/AJNT.AJNT_9_26
Abstract
Pancytopenia results from diverse underlying conditions. Parvovirus B19 can directly suppress bone marrow and mimic sepsis or drug-induced cytopenia. We report a patient with chronic kidney disease, predialysis, and managed conservatively, who presented with fever and pyelonephritis. Methotrexate use for arthritis initially suggested drug toxicity, but bone marrow aspiration and biopsy revealed features consistent with parvovirus infection, later confirmed by molecular testing. This case highlights the importance of early bone marrow aspirate and biopsy in considering parvovirus B19 in unexplained pancytopenia, thereby enabling timely diagnosis.
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The Arab Journal of Nephrology and Transplantation is the peer-reviewed open-access journal of ASNRT, published since 2008.
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