Vancomycin AUC24 / MIC Calculator
Two-level vancomycin AUC24 exposure estimate (ASHP/IDSA 2020)
When to use it
Use for steady-state AUC24 monitoring with stable clearance; 400–600 mg·h/L applies to serious MRSA assuming MIC 1 mg/L.
Category
Drug Dosing & Toxicity
References
- Rybak MJ et al. Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists. Am J Health Syst Pharm. 2020;77:835-864. PMID: 32191793
- Neely MN et al. Prospective Trial on the Use of Trough Concentration versus Area under the Curve To Determine Therapeutic Vancomycin Dosing. Antimicrob Agents Chemother. 2018;62:e02042-17. PMID: 29203493
About NephroMind
This calculator is part of NephroMind, a free clinical decision-aid platform from the Arab Society of Nephrology and Renal Transplantation (ASNRT) — over 128 bedside nephrology calculators plus a renal drug-dosing database, coded by a practicing transplant nephrologist.