KDPI Calculator — Kidney Donor Profile Index (2024 Refit)
Convert deceased-donor characteristics into a Kidney Donor Profile Index (KDPI) percentile, a 0 to 100 percent estimate of donor kidney quality relative to last year's recovered kidneys, using the OPTN 2024 Refit model (eight factors, no race or HCV) that drives deceased-donor allocation sequences A to D.
When to use it
Use to assess deceased-donor kidney quality during organ-offer decisions, to pair low-KDPI kidneys with low-EPTS recipients (longevity matching), and to inform recipient counseling. Do not use as a sole accept-or-reject criterion (C-statistic about 0.60).
Formula
Inputs: donor age, height, weight, serum creatinine, history of hypertension and diabetes, cause of death, and DCD status (eight factors). The KDRI is computed then mapped to a KDPI percentile against the reference population.
Category
Transplantation
References
- OPTN. A Guide to Calculating and Interpreting the Kidney Donor Profile Index (KDPI). Updated: April 23, 2026. HRSA. https://www.hrsa.gov/sites/default/files/hrsa/optn/kdpi_guide.pdf
- OPTN. KDRI to KDPI Mapping Table. Based on the OPTN database as of April 03, 2026. HRSA. https://www.hrsa.gov/sites/default/files/hrsa/optn/kdpi_mapping_table.pdf
- Miller JM et al. Updating the kidney donor risk index: Removing donor race and hepatitis C virus status. Am J Transplant. 2025;25:1245-1252. PMID: 39832693
Common clinical questions
- Should I decline a high-KDPI kidney offer?
- Not on KDPI alone. KDPI estimates donor quality but discriminates only modestly (C-statistic about 0.60), so a high-KDPI kidney can still benefit an older or higher-EPTS recipient for whom the alternative is prolonged dialysis. Weigh KDPI with the candidate's waiting time, dialysis vintage, and expected wait for a better offer.
About NephroMind
This calculator is part of NephroMind, a free clinical decision-aid platform from the Arab Society of Nephrology and Renal Transplantation (ASNRT) — over 128 bedside nephrology calculators plus a renal drug-dosing database, coded by a practicing transplant nephrologist.