Anticoagulation Reversal Guide Calculator
Evidence-based reversal strategies for major bleeding
When to use it
Use to determine the appropriate reversal agent and dosing for major bleeding on anticoagulants.
Category
Drug Dosing & Toxicity
References
- Tomaselli GF et al. 2020 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2020;76:594-622. PMID: 32680646
- Frontera JA et al. Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage: A Statement for Healthcare Professionals from the Neurocritical Care Society and Society of Critical Care Medicine. Neurocrit Care. 2016;24:6-46. PMID: 26714677
- Cuker A et al. Reversal of direct oral anticoagulants: Guidance from the Anticoagulation Forum. Am J Hematol. 2019;94:697-709. PMID: 30916798
- FDA. Update on the Safety of Andexxa. FDA Safety Communication, December 18, 2025. https://www.fda.gov/vaccines-blood-biologics/safety-availability-biologics/update-safety-andexxa
About NephroMind
This calculator is part of NephroMind, a free clinical decision-aid platform from the Arab Society of Nephrology and Renal Transplantation (ASNRT) — over 128 bedside nephrology calculators plus a renal drug-dosing database, coded by a practicing transplant nephrologist.