Spot Protein/Albumin Ratio (24-hour context) Calculator
Reports a spot albumin/protein ratio with limitations of daily-excretion estimates
When to use it
Use to report a spot albumin/protein ratio and understand the limits of approximating daily excretion.
Category
Proteinuria & Glomerular Disease
References
- KDIGO CKD Work Group. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int. 2024;105(4S):S117-S314. https://kdigo.org/guidelines/ckd-evaluation-and-management/
- Forni Ogna V et al. New anthropometry-based age- and sex-specific reference values for urinary 24-hour creatinine excretion based on the adult Swiss population. BMC Med. 2015;13:40. PMID: 25858764
- Ginsberg JM et al. Use of single voided urine samples to estimate quantitative proteinuria. N Engl J Med. 1983;309:1543-6. PMID: 6656849
- Ledesma G et al. Comparison of 24-Hour Proteinuria Quantification With Protein-to-Creatinine Ratio in Spot Urine and Protein-to-Creatinine Ratio Adjusted to Estimated Creatinine Excretion Rate in Kidney Transplant Recipients. Transplant Proc. 2026;58:249-251. PMID: 41672850
- Kobayashi S et al. Spot urine protein/creatinine ratio as a reliable estimate of 24-hour proteinuria in patients with immunoglobulin A nephropathy, but not membranous nephropathy. BMC Nephrol. 2019;20:306. PMID: 31387546
- Díaz Enamorado Y et al. MO377: Correlation Between 24-H Proteinuria and Spot Urine Albumin-Creatinine Ratio in Biopsy-Proven Glomerular Diseases. Nephrol Dial Transplant. 2022;37(Suppl 3) (conference abstract; no PMID). doi:10.1093/ndt/gfac069.010
- Joshi KR et al. Correlation between spot urine protein creatinine ratio and 24-hour urinary protein in systemic lupus erythematosus patients with proteinuria. J Gen Pract Emerg Med Nepal. 2025;12(19):53-58 (not indexed in PubMed). doi:10.59284/jgpeman344
- Huang Y et al. Correlation of urine protein/creatinine ratios to 24-h urinary protein for quantitating proteinuria in children. Pediatr Nephrol. 2020;35:463-468. PMID: 31813022
- Floyd L et al. Testing the waters on home-based albuminuria screening to enhance the detection and management of CKD. Clin Kidney J. 2024;17:sfae031. PMID: 38410686
About NephroMind
This calculator is part of NephroMind, a free clinical decision-aid platform from the Arab Society of Nephrology and Renal Transplantation (ASNRT) — over 128 bedside nephrology calculators plus a renal drug-dosing database, coded by a practicing transplant nephrologist.